Tissue Allograft Therapy & Scar Tissue

The human body often has everything necessary to produce real healing after an injury. Unfortunately these amazing things can produce Scar Tissue. 

Scar tissue forms because of the body healing itself from an injury. Essentially the body will fill the gap with new tissue around the damaged site, and these scars can come in all sorts of sizes and shapes. From large and painful scars, to small and not-so-noticeable. 

However, for some people, these scars never go away. In fact, they can be a permanent reminder of a painful past many people would probably rather forget. 

The good news? 

This doesn’t have to be the case anymore. Enter regenerative tissue allograft therapy which has emerged as a rather revolutionary approach to healing. And one area where tissue allograft therapy is showing significant promise is in helping treat scar tissue. 

Today we’re going to dive headfirst into this exciting link between tissue allograft therapy and scar tissue treatment. Our goal is to showcase how this cutting-edge field is producing real transformation to those individuals affected by scars – whether it’s from pesky acne to deep surgical scars – helping to redefine beauty for those in pain.

Tissue Allograft Therapy Scar Treatment: A Quick Guide

To understand if tissue allograft therapy can help scar treatment, we need to first break down how scars form. 

Essentially you can summarize wound healing into three primary processes: 

  1. Inflammation – this will happen for the first 72 hours of the injury with the main goal of clearing out bacteria and debris from the wound. This is where the wound will feel warm and red due to increased blood flow. 
  2. Proliferation – this is the period where new type 3 collagen tissue is formed to help replace the damaged area (which is usually composed of type 1 collagen). 
  3. Remodeling – at this point your body will try to convert the type 3 collagen back to type 1 collagen (which is when you may get normal appearance) but it will never get back to full normal production and will be consistently weaker than normal tissue. 

At each of these stages tissue allograft therapy can provide assistance to the body for regenerating normal tissue instead of scar tissue. 

How is this accomplished? Because of two primary factors:

  1. Reduced Inflammation

    Almost immediately after an injury, your body will begin to produce signals to promote inflammation. These signals come from cytokines which can be both inflammatory and anti-inflammatory. In the context of scar tissue forming, it’s the inflammatory cytokines which signal cells to begin forming collagen 3 structures for scar tissue. However, studies have shown that by introducing tissue allograft, the damaged tissue won’t generate as much inflammatory cytokines, and there’s even evidence that it will produce anti-inflammatory cytokines which signals to the body to form normal skin tissue.

  2. Paracrine Signaling

    There’s a growing body of evidence indicating that tissue allograft helps induce paracrine signaling for the assistance in wound healing. Basically paracrine signaling is a form of communication between the cells to help in producing differentiation. When tissue allografts are introduced to a damaged tissue site, let’s say deep acne, for instance, there’s a signal produced which works to help the damaged tissue differentiate into proper skin cells (including hair follicles, sweat glands, and subcutaneous tissue).

With these two primary processes, tissue allograft therapy is helping provide an outlet for transformation of scar tissue into normal working tissue. 

Final Thoughts

Hopefully this has provided some insights into the world of wound healing. Whether you’re dealing with acne caused facial scarring, or you have surgical scars you would like to help heal, consider tissue allograft therapy as an innovative outlet way to regeneration.